Norcucurbitane Triterpenoids from the Fruits of Momordica charantia var. abbreviata

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Cucurbitane-type triterpenoids from the stems of momordica charantia.

Four new cucurbitane-type triterpenes, cucurbita-5,23(E)-diene-3beta,7beta,25-triol (1), 3beta-acetoxy-7beta-methoxycucurbita-5,23(E)-dien-25-ol (2), cucurbita-5(10),6,23(E)-triene-3beta,25-diol (5), and cucurbita-5,24-diene-3,7,23-trione (6), together with four known triterpenes, 3beta,25-dihydroxy-7beta-methoxycucurbita-5,23(E)-diene (3), 3beta-hydroxy-7beta,25-dimethoxycucurbita-5,23(E)-dien...

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New cucurbitane triterpenoids and steroidal glycoside from Momordica charantia.

Three new cucurbitane triterpenoids 1-3 and one new steroidal glycoside 4, were isolated together with ten known compounds from Momordica charantia. The structures of new compounds were determined to be 19(R)-n-butanoxy-5 beta,19-epoxycucurbita-6,23-diene-3beta,25-diol 3-O-beta-glucopyranoside (1), 23-O-beta-allopyranosylecucurbita-5,24-dien-7 alpha,3beta,22(R),23(S)-tetraol 3-O-beta-allopyrano...

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Enzymatic Activity of Momordica Charantia Fruits

The crude enzyme fraction was isolated from the fresh unripe fruits of Momordica charantia Linn and screened for its amylolytic and lipolytic activity according to standard literatures. The results indicated that the crude enzyme fraction is having effective amylolytic and lipolytic activities. These enzymatic activitieis of the extract substantiate the validity of claims made in traditional sy...

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Cucurbitane-Type Triterpenoids from the Blood Glucose-Lowering Extracts of Coccinia indica and Momordica balsamina Fruits

CONTEXT Few vegetables that are commonly consumed in India as part of diet have been claimed for their antidiabetic potential. OBJECTIVE The present study was aimed at evaluating preventive effects of cucurbit vegetables namely, Coccinia indica and Momordica balsamina belonging to family Cucurbitaceae in diabetic hyperglycemia. MATERIALS AND METHODS The fruits of M. balsamina and C. indica ...

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Treating Hyperinsulinemia with Momordica charantia

Objectives: To assess the efficacy of a novel nutraceutical mainly containing the extract of bitter gourd (Momordica charantia) and α-lipoic acid for the treatment of patients with hyperinsulinemia. Methods: Pilot prospective open-label cohort trial including 11 patients with hyperinsulinemia due to insulin resistance. The concentrations of insulin, C-peptide, glucose, haemoglobin A1c, total ch...

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ژورنال

عنوان ژورنال: Natural Product Communications

سال: 2013

ISSN: 1934-578X,1555-9475

DOI: 10.1177/1934578x1300800119